Cortical and non-cortical myoclonus of Creutzfeldt-Jakob disease.

B, vasculitis, and syphilis was excluded by the results of biochemical screening tests. EEGs showed PSDs with the largest amplitude over the central parietal area of the right hemisphere (i.e. C4 and P4; fig. 1 a). Magnetic resonance imaging study showed restricted diffusion over the right frontal, parietal, and occipital lobes in diffusionweighted imaging (DWI) ( fig. 1 b). 99m TcTRODAT-1 revealed a bilateral decrease in striatal uptake values ( fig. 1 c). The patient’s symptoms continuously deteriorated. The patient became bedridden, and showed akinetic mutism and loss of swallowing capabilities at around 2.5 months after the disease onset. According to WHO criteria (1998), probable CJD was diagnosed. The WHO criteria had a diagnostic accuracy of 96.5% in a follow-up study performed in 313 patients [1] . Protein 14-3-3 was absent in 9.9% of the patients diagnosed with probable CJD on the basis of the criteria [1] .